Chronic remitting pouchitis


Inflammatory Bowel Disease (IBD) collectively refers to Crohn’s disease and Ulcerative colitis, chronic autoimmune conditions in which the body’s immune system attacks the mucosal lining of the gastro-intestinal system. Alicaforsen utilizes a technology called anti-sense RNA, to suppress the cellular expression of a key protein in the inflammatory cascade, ICAM-1, thereby reducing inflammation. Alicaforsen is administered as a rectal solution, thus focusing its effect locally in the area of disease without significant systemic exposure.